The Midlifesy wellness blog

Smarter midlife health, without the generic advice.

Jamie’s complete archive brings current, evidence-informed guidance together with practical perspective on hormones, metabolism, energy, body composition, sleep, and life in your forties and beyond.

88 articles · Read · Reflect · Ask better questions
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From Jamie’s desk

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One thoughtful library.

Browse all 88 Midlifesy posts—now gathered into one searchable, native reading experience.

Showing 88 of 88 articles

02

Metabolic health · September 9, 2026

PCOS Just Became PMOS. Here's Why That Matters: The name change that finally admits it was never really about ovarian cysts

Discover why PCOS is being reexamined as a systemic metabolic condition and what the shift to PMOS could mean for women’s health and care.

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03

Metabolic health · September 7, 2026

Metabolic Flexibility: Why Your Body Forgot How to Switch Fuel Sources (and How to Retrain It)

Learn what metabolic flexibility is, why it declines with age, and how nutrition, exercise, sleep, stress, and strength training can help restore it.

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04

Hormones · September 1, 2026

Low-Dose Naltrexone in Perimenopause: What You Should Know

Learn how low-dose naltrexone (LDN) may support women in perimenopause with inflammation, pain, sleep, mood, and lingering symptoms.

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05

Midlife wellness · August 26, 2026

Why Your Labs Came Back “Normal” But You Still Feel Terrible

Your labs may be “normal,” but that doesn’t mean you feel your best. Learn which overlooked labs and patterns may help explain your symptoms.

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06

Metabolic health · July 21, 2026

What GLP-1 Medications Actually Do Beyond Weight Loss — And Why That Matters

Learn how GLP-1 medications support metabolism, liver health, insulin sensitivity, heart health, and appetite regulation—beyond weight loss.

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07

Metabolic health · July 14, 2026

What PCOS, PMDD, and Perimenopause Have in Common — And Why It Matters

Discover how PCOS, PMDD, and perimenopause are connected through hormones, insulin resistance, and inflammation—and why treating the whole system matters.

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08

Hormones · June 15, 2026

Why Your Hormone Therapy Feels Different in Summer

Summer changes can affect how your body responds to hormone therapy. Learn why symptoms shift seasonally and what it means for your treatment.

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09

Hormones · June 8, 2026

The Conversation No One Wants to Have

Midlife intimacy changes are often physiological—not personal. Learn how hormones, stress, and health affect desire and why avoiding the conversation matters.

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10

Metabolic health · June 1, 2026

When Convenience Starts Working Against Your Metabolism

Learn how processed foods, inflammation, and blood sugar swings affect metabolism, hormones, energy, and weight in midlife women.

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11

Hormones · May 26, 2026

The Invisible Shift of Perimenopause

Learn the early signs of perimenopause, from brain fog and poor sleep to mood swings and fatigue, and why so many women feel “off” in midlife.

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12

Metabolic health · April 20, 2026

Inflammation: The Metabolic Blocker That Doesn’t Show Up on the Scale

Chronic inflammation can stall fat loss and disrupt metabolism. Learn why the scale doesn’t reflect progress—and how to fix it.

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Articles are educational and do not replace individualized medical evaluation or advice.